Objectives: To assess residual long-term microcirculation abnormalities by capillaroscopy, 15 years after retiring from occupational exposure to vinyl chloride monomer (VCM). It has a mild, sweet odor. 9.2.2 Inhalation Repeated exposure to vinyl chloride may induce vinyl chloride disease which is characterized by scleroderma-like changes of the fingers, Raynaud's phenomenon and acro-osteolysis. Function tests of bone marrow, liver, kidney, and nerves may be useful in determining the effects of vinyl chloride exposure. Ataxia. time-related exposure response. There are a number of ways in which a person can become exposed to vinyl chloride, including through: Inhalation; Drinking contaminated water; Work - people who work with vinyl chloride are at the highest risk of vinyl chloride exposure Chronic (long-term) exposure to vinyl chloride through Vinyl Chloride is used mainly to make PVC products. Objectives To assess residual long-term microcirculation abnormalities by capillaroscopy, 15 years after retiring from occupational exposure to vinyl chloride monomer (VCM). This report details the investigation of exposures and symptoms … Health effects may occur from exposure to vinyl chloride at concentrations below the odor threshold. While these were prevalent in extraordinary amounts in the groundwater and soil for decades at […] Reply. Acute (short-term) exposure to high levels of vinyl chloride in air has resulted in central nervous system effects (CNS), such as dizziness, drowsiness, and headaches in humans. Symptoms of Vinyl Chloride Exposure. Reproductive toxicity -- Vinyl Chloride: Vinyl Chloride is a suspected reproductive toxicant and exposure to it has the potential to negatively affect the human reproductive system. Toxic Exposure Injury Attorneys - Serving Clients Nationwide. PVC comes in two basic forms: rigid … 9.2 Chronic poisoning 9.2.1 Ingestion Not reported. This test is not routinely available at most medical facilities, and its results may not accurately reflect the level or the duration of the exposure. Frequency of the arterial hypertension was the same in both groups, whereas acroparesthesias, Raynaud's syndrome, and increased gamma GTP serum activity were significantly more frequent in workers with neurological disturbances. There are certain symptoms that are likely to appear if you have been exposed to vinyl chloride. [ifediba.com] The gas can cause dizziness, drowsiness, and headache when inhaled. In 2012 in New Jersey, a train derailment resulted in the puncture of a tanker car carrying liquid vinyl chloride under pressure, and a resulting airborne vinyl chloride plume drifted onto the grounds of a nearby refinery. INTRODUCTION Vinyl chloride monomer (VCM) is primarily used in the manufacture of plastics and also serves as a raw material in organic synthesis. TO VINYL CHLORIDE FINAL REPORT SCIENCE APPLICATIONS, INC, 1801 AVENUE OF THE STARS SUITE 1205 Los ANGELES, CALIFORNIA 90067 . Additionally, there are reports of cases of significant chronic exposure related to aerosol propellant usage in the 1960s and early 1970s, although VCM is no longer utilized in this manner. Treatment of exposure should be directed at the control of symptoms and the clinical condition of the patient. Reported New or Worsened Symptoms Overall, 58% of participants in the In-Person Survey and 66% in the Mailed Survey reported experiencing new or worsening symptoms in … Vinyl chloride (Figure 8.2), which is produced for industrial use as a chemical intermediate in the manufacture of other compounds, particularly polyvinyl chloride (PVC), is toxic by all routes of exposure. Inebriation. Vinyl chloride can be found in urine and body tissues after recent exposures. Vinyl-chloride disease is, however, clinically very similar to scleroderma, and the observations by ourselves and others that susceptibility to scleroderma is linked, albeit weakly, to HLA markers4-6 led us to study 44 of the 53 patients with symptoms of vinyl-chloride disease originally described by Ward et al. Occupational exposure to vinyl chloride was lower in workers without neurological findings. Design: Cross-sectional study. Vinyl chloride is a respiratory irritant producing coughing, wheezing and breathlessness. It can be formed when other substances such as trichloroethane, trichloroethylene, and tetrachloroethylene are broken down. It is metabolized to the active metabolites chloroethylene oxide and chloracetaldehyde, which is responsible for its toxicity. 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